Conduct foundational research to identify the ALS disease mechanism and ALS biomarkers to enable pharmaceutical and biotechnology companies to develop the ALS cure.
ALS CURE Project was founded in 2019 by Mike Piscotty and Stephen Piscotty in honor of Gretchen Piscotty with the sole purpose of finding a cure for ALS.
There are two key challenges in developing an ALS cure: the ALS disease mechanism and ALS biomarkers are unknown. This is compounded by the reality that the revenue opportunity for pharmaceutical companies is limited as only 18,000 people in United States have the disease at a given time compared to the 2 million people battling cancer. Unfortunately, due to a lack of a diagnostic test for ALS, a patient typically has to endure multiple uncomfortable nerve tests in addition to several tests for MS, AIDS, Parkinson’s Disease, Lime Disease, and heavy metals poisoning. As ALS progresses, it attacks the motor neurons throughout the body immobilizing the patient, ultimately resulting in an inability to breathe.
Through identifying the ALS disease mechanism, our research will help develop a cure for ALS. The successful identification of the ALS disease mechanism is the first step in identifying progression, diagnostic, and prognostic ALS biomarkers. The diagnostic biomarker will help develop a diagnostic test that will promptly and accurately diagnose patients with ALS so they can begin treatment immediately.
A day when a person contracting ALS, is quickly diagnosed, treated with the ALS cure to stop progression.